Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release.

@article{Almada2016AnandamideIW,
  title={Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release.},
  author={Marta Almada and Sara Cristina Cunha and Bruno M. Fonseca and Cristina Amaral and Fabiana Piscitelli and Vincenzo Di Marzo and Georgina Correia-da-Silva and Nat{\'e}rcia Teixeira},
  journal={BioFactors},
  year={2016},
  volume={42 3},
  pages={
          277-86
        }
}
The human endometrium undergoes cyclical growth, differentiation, and regression periods throughout the reproductive life. The process in which endometrial stromal cells proliferate and differentiate into decidual cells, named decidualization, prepares a receptive endometrium for implantation. Prostaglandins (PGs) and endocannabinoids (eCBs) are crucial mediators of this process. We have recently reported that the eCB anandamide (AEA) interferes with rat stromal cell differentiation, and on the… 

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