Analyzing temozolomide medication errors: potentially fatal

Abstract

The EORTC–NCIC regimen for glioblastoma requires different dosing of temozolomide (TMZ) during radiation and maintenance therapy. This complexity is exacerbated by the availability of multiple TMZ capsule strengths. TMZ is an alkylating agent and the major toxicity of this class is dose-related myelosuppression. Inadvertent overdose can be fatal. The… (More)
DOI: 10.1007/s11060-014-1523-1

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