Analyzing motion and deformation of the cell nucleus for studying co-localizations of nuclear structures

@article{Mattes2006AnalyzingMA,
  title={Analyzing motion and deformation of the cell nucleus for studying co-localizations of nuclear structures},
  author={Julian Mattes and Janna Nawroth and Petra Boukamp and Roland Eils and Karin M. Greulich-Bode},
  journal={3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006.},
  year={2006},
  pages={1044-1047}
}
In cell biology, modern imaging techniques using fluorescence microscopy allow to visualize specific nuclear structures in situ in the same cell nucleus. Hence, distances between these structures can be evaluated, in particular co-localization can be investigated. When the nucleus alters its global shape, especially if the structures are imaged sequentially, the distances are changing as well and the global movements have to be compensated. In this paper we present an image processing based… CONTINUE READING
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