Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation.

@article{Durbin2015AnalyzingIF,
  title={Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation.},
  author={Kenneth R. Durbin and Owen S Skinner and Ryan T. Fellers and Neil L. Kelleher},
  journal={Journal of the American Society for Mass Spectrometry},
  year={2015},
  volume={26 5},
  pages={782-7}
}
Gaseous fragmentation of intact proteins is multifaceted and can be unpredictable by current theories in the field. Contributing to the complexity is the multitude of precursor ion states and fragmentation channels. Terminal fragment ions can be re-fragmented, yielding product ions containing neither terminus, termed internal fragment ions. In an effort to better understand and capitalize upon this fragmentation process, we collisionally dissociated the high (13+), middle (10+), and low (7… CONTINUE READING