Analyzing autophagy in clinical tissues of lung and vascular diseases.

Abstract

Autophagy, a process by which organelles and cellular proteins are encapsulated in double-membrane vesicles and subsequently degraded by lysosomes, plays a central role in cellular and tissue homeostasis. In various model systems, autophagy may be triggered by nutrient deprivation, oxidative stress, and other insults such as endoplasmic reticulum stress… (More)
DOI: 10.1016/S0076-6879(08)04010-X

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