Analyzing Effects of Naturally Occurring Missense Mutations

  title={Analyzing Effects of Naturally Occurring Missense Mutations},
  author={Zhe Zhang and Maria A. Miteva and Lin Wang and Emil Alexov},
  booktitle={Comp. Math. Methods in Medicine},
Single-point mutation in genome, for example, single-nucleotide polymorphism (SNP) or rare genetic mutation, is the change of a single nucleotide for another in the genome sequence. Some of them will produce an amino acid substitution in the corresponding protein sequence (missense mutations); others will not. This paper focuses on genetic mutations resulting in a change in the amino acid sequence of the corresponding protein and how to assess their effects on protein wild-type characteristics… CONTINUE READING


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