Analytical methods to investigate glutathione and related compounds in biological and pathological processes.

@article{Camera2002AnalyticalMT,
  title={Analytical methods to investigate glutathione and related compounds in biological and pathological processes.},
  author={Emanuela Camera and Mauro Picardo},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2002},
  volume={781 1-2},
  pages={181-206}
}
Reduced glutathione (GSH, gamma-L-glutamyl-L-cysteinylglycine) is a fundamental low-molecular mass antioxidant that serves several biological functions. Upon enzymatic and non-enzymatic oxidation, GSH forms glutathione disulfide (GSSG) and, under particular conditions, may generate other oxidative products. The determination of GSH, its precursors, and metabolites in several bio-matrices is a useful tool in studying oxidative stress. Many separative and non-separative methods have been… CONTINUE READING

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