Analytical methods for the quality control of Prozac capsules.

@article{Raggi1998AnalyticalMF,
  title={Analytical methods for the quality control of Prozac capsules.},
  author={Maria Augusta Raggi and Francesca Bugamelli and G. Casamenti and Roberto Mandrioli and Diana De Ronchi and V. Volterra},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={1998},
  volume={18 4-5},
  pages={
          699-706
        }
}
Some analytical methods (two spectrophotometric and two chromatographic procedures) for the determination of fluoxetine in Prozac capsules are described. All of them are applied to the samples after extracting the drug with a methanol water mixture. The direct and derivative spectrophotometric methods are simple and reliable; the derivative method gives better recovery and lessens interference. Both methods show linearity in the 5-30 microg ml(-1) range of the fluoxetine concentration range… CONTINUE READING

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