Analytical challenges of extracellular vesicle detection: A comparison of different techniques.

@article{Erdbrgger2016AnalyticalCO,
  title={Analytical challenges of extracellular vesicle detection: A comparison of different techniques.},
  author={Uta Erdbr{\"u}gger and Joanne A. Lannigan},
  journal={Cytometry. Part A : the journal of the International Society for Analytical Cytology},
  year={2016},
  volume={89 2},
  pages={123-34}
}
The interest in extracellular vesicles (EVs) has grown exponentially over the last decade. Evolving evidence is demonstrating that these EVs are playing an important role in health and disease. They are involved in intercellular communication and have been shown to transfer proteins, lipids, and nucleic acids. This review focuses on the most commonly used techniques for detection of EVs, to include microparticles, 100-1,000 nm in size, and exosomes, 50-100 nm in size. Conventional flow… CONTINUE READING
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