Analytical Biases Associated with GC-Content in Molecular Evolution

Abstract

Molecular evolution is being revolutionized by high-throughput sequencing allowing an increased amount of genome-wide data available for multiple species. While base composition summarized by GC-content is one of the first metrics measured in genomes, its genomic distribution is a frequently neglected feature in downstream analyses based on DNA sequence… (More)
DOI: 10.3389/fgene.2017.00016

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