Analytic approaches to differential gene expression in AIDS versus control brains.

@article{Shapshak2004AnalyticAT,
  title={Analytic approaches to differential gene expression in AIDS versus control brains.},
  author={Paul Shapshak and Robert A Duncan and Jorge E. Torres-Mu{\~n}oz and Elda Margarita Duran and Alireza Minagar and Carol K. Petito},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2004},
  volume={9},
  pages={2935-46}
}
We previously showed that specific strains of human immunodeficiency virus (HIV)-1 infect the brain and contribute to Neuropathology, Cognitive Distress, and Neuropsychiatric Disease. To study further brain disease that results from HIV-1 infection, we commenced analysis of changes in gene expression in brain. We analyzed RNA purified from Frontal Cortex of 5 HIV-1 infected and 4 HIV-1 negative control subjects RNA was amplified and Affymetrix technology was used to analyze gene expression… CONTINUE READING
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