Analytic approaches to differential gene expression in AIDS versus control brains.

  title={Analytic approaches to differential gene expression in AIDS versus control brains.},
  author={Paul Shapshak and Robert A Duncan and Jorge E. Torres-Mu{\~n}oz and Elda Margarita Duran and Alireza Minagar and Carol K. Petito},
  journal={Frontiers in bioscience : a journal and virtual library},
We previously showed that specific strains of human immunodeficiency virus (HIV)-1 infect the brain and contribute to Neuropathology, Cognitive Distress, and Neuropsychiatric Disease. To study further brain disease that results from HIV-1 infection, we commenced analysis of changes in gene expression in brain. We analyzed RNA purified from Frontal Cortex of 5 HIV-1 infected and 4 HIV-1 negative control subjects RNA was amplified and Affymetrix technology was used to analyze gene expression… CONTINUE READING
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Effects of cocaethylene on surface marker expression of HIV-1 infected macrophages isolated from human brain using antibody-coated magnetic beads: a preliminary study

  • RV Stewart, P. Shapshak, +10 authors J. C. Arguello
  • Vision Research (A Journal of Morphology), 4, 66…
  • 1997
Highly Influential
4 Excerpts

A gender comparison of HIV and drug use across the rural urban continuum

  • CB McCoy, L. R. Metsch, H. V. McCoy, S. Lai
  • Popul Res and Policy Rev, 18, 71-87
  • 1999
Highly Influential
4 Excerpts

Drug use and risk of AIDS

  • CB McCoy, E. Khoury
  • Am Behav Sci, 33, 419-31
  • 1990
Highly Influential
4 Excerpts

Petito: RNA preservation in post-mortem cerebral cortex of AIDS and control brains

  • J Torres-Muñoz, P. Shapshak, R. Polavarapu, M. Bowman, M. Keegan, C.K
  • J Neurovirol. In press,
  • 2004
2 Excerpts

Chapter 8

  • W Valdivia Granda
  • Strategies of clustering, classifying…
  • 2003
2 Excerpts

Chapter 8 . Strategies of clustering , classifying , integrating , standardizing , and visualizing MicroArray gene expression data

  • W ValdiviaGranda
  • A Beginner ’ s guide to Microarrays
  • 2003

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