Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor.

@article{Zhao2011AnalyteinducedFO,
  title={Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor.},
  author={Yongxi Zhao and Xi-wen He and Xue-Bo Yin},
  journal={Chemical communications},
  year={2011},
  volume={47 22},
  pages={6419-21}
}
Analyte-induced formation of partial duplexes was used for biosensor development with cocaine as a model. The cocaine-aptamer interaction resulted in formation of a partial double strand section in the aptamer, where Ru(phen)(3)(2+) was intercalated for electrochemiluminescent analysis of cocaine. 

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