Analysis of whole genomic expression profiles and screening of the key signaling pathways associated with pancreatic cancer.

@article{He2012AnalysisOW,
  title={Analysis of whole genomic expression profiles and screening of the key signaling pathways associated with pancreatic cancer.},
  author={Chengzhi He and Hua Jiang and Shasha Geng and Haihui Sheng and Xiaoying Shen and Xiaoyan Zhang and Shizhang Zhu and Ximei Chen and Changqing Yang and Hengjun Gao},
  journal={International journal of clinical and experimental pathology},
  year={2012},
  volume={5 6},
  pages={
          537-46
        }
}
The tumorigenesis of pancreatic cancer is thought to be a complex process. Investigation of the molecular mechanism of pancreatic cancer and exploring the specific markers for early diagnosis and specific targets of therapy is a key point to prevent and treat pancreatic cancer effectively and to improve their prognosis. In this study, expression profiles experiment was performed using Agilent human whole genomic oligonucleotide microarrays with 41,000 genes. Differentially expressed genes… CONTINUE READING