Analysis of treatment failure in acute nonlymphocytic leukemia patients over fifty years of age. A Southwest Oncology Group study.

@article{Ryan1992AnalysisOT,
  title={Analysis of treatment failure in acute nonlymphocytic leukemia patients over fifty years of age. A Southwest Oncology Group study.},
  author={Donna H Ryan and Kenneth J. Kopecky and David Pesetsky Head and Michael R Grever and S M Shiaer and David A. Lipschitz and Harry E. Hynes and Remi Vial and Robert W Veith and C H Gumbart},
  journal={American journal of clinical oncology},
  year={1992},
  volume={15 1},
  pages={69-75}
}
Fourteen participating centers registered 33 patients on a Southwest Oncology Group Study of adults with acute non-lymphocytic leukemia (ANLL). Induction consisted of cytosine arabinoside 70 mg/m2 days 1-7 by continuous intravenous (i.v.) infusion, VP-16 50 mg/m2 i.v. over 1 hour days 1-3, and daunomycin 30 mg/m2 i.v. bolus days 1-3. Twenty-five patients (median age 69 years) were evaluable for response. Eleven (44%) achieved a remission marrow but only 8 fulfilled both blood and marrow… CONTINUE READING