Analysis of transcriptional regulation of the small leucine rich proteoglycans.

  title={Analysis of transcriptional regulation of the small leucine rich proteoglycans.},
  author={Elena S. Tasheva and Bernward Klocke and Gary Conrad},
  journal={Molecular vision},
PURPOSE Small leucine rich proteoglycans (SLRPs) constitute a family of secreted proteoglycans that are important for collagen fibrillogenesis, cellular growth, differentiation, and migration. Ten of the 13 known members of the SLRP gene family are arranged in tandem clusters on human chromosomes 1, 9, and 12. Their syntenic equivalents are on mouse chromosomes 1, 13, and 10, and rat chromosomes 13, 17, and 7. The purpose of this study was to determine whether there is evidence for control… CONTINUE READING
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