Analysis of the yeast kinome reveals a network of regulated protein localization during filamentous growth.

@article{Bharucha2008AnalysisOT,
  title={Analysis of the yeast kinome reveals a network of regulated protein localization during filamentous growth.},
  author={Nik{\"e} Bharucha and Jun Ma and Craig J. Dobry and Sarah K Lawson and Zhifen Yang and Anuj Kumar},
  journal={Molecular biology of the cell},
  year={2008},
  volume={19 7},
  pages={
          2708-17
        }
}
The subcellular distribution of kinases and other signaling proteins is regulated in response to cellular cues; however, the extent of this regulation has not been investigated for any gene set in any organism. Here, we present a systematic analysis of protein kinases in the budding yeast, screening for differential localization during filamentous growth. Filamentous growth is an important stress response involving mitogen-activated protein kinase and cAMP-dependent protein kinase signaling… CONTINUE READING
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