Analysis of the role of chemokines in angiogenesis.

  title={Analysis of the role of chemokines in angiogenesis.},
  author={Giovanni Bernardini and Domenico Ribatti and G Spinetti and Lucia Morbidelli and Marina Ziche and Angela Santoni and Maurizio Colognesi Capogrossi and Monica Napolitano},
  journal={Journal of immunological methods},
  volume={273 1-2},
Chemokines, a large family of inflammatory cytokines, have been shown to play a critical role in the regulation of angiogenesis during several pathophysiologic processes, such as tumor growth, wound healing and ischemia. Semiquantitative or quantitative angiogenesis assays are commonly utilized to screen the angiogenic or angiostatic activity of chemokines. These include in vitro endothelial cell activation assays and ex vivo or in vivo models of neovascularization. Chemokines may exert their… CONTINUE READING

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