Analysis of the relationship between radiosensitivity and cell age in proliferating mouse spleen lymphocytes.


The radiosensitivity of the first cell cycle in mouse lymphocytes was compared to that of the later cell cycles by means of analysis of chromatid-type aberrations. A nearly pure population of first-division metaphases (M1) was obtained when lymphocytes were harvested 28 h after stimulation. When the cells were fixed at 52 h of culture time, approximately 90… (More)


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