Analysis of the reactions used for the preparation of drug candidate molecules.

  title={Analysis of the reactions used for the preparation of drug candidate molecules.},
  author={John S. Carey and David Dermot Patrick Laffan and Colin Thomson and Michael Trevelyan Williams},
  journal={Organic \& biomolecular chemistry},
  volume={4 12},
The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer. 
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