Analysis of the reactions used for the preparation of drug candidate molecules.

  title={Analysis of the reactions used for the preparation of drug candidate molecules.},
  author={J. S. Carey and D. Laffan and C. Thomson and Mike Williams},
  journal={Organic & biomolecular chemistry},
  volume={4 12},
  • J. S. Carey, D. Laffan, +1 author Mike Williams
  • Published 2006
  • Chemistry, Medicine
  • Organic & biomolecular chemistry
  • The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer. 
    1,096 Citations
    Applying homogeneous catalysis for the synthesis of pharmaceuticals.
    • M. Beller
    • Chemistry, Medicine
    • Ernst Schering Foundation symposium proceedings
    • 2006
    Drug discovery chemistry: a primer for the non-specialist.
    • 26
    • PDF
    Catalysis: The pharmaceutical perspective
    • 13
    The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates.
    • 849
    • PDF


    Industrial methods for the production of optically active intermediates.
    • 990
    Protecting Groups in Organic Synthesis
    • 491
    • PDF