Analysis of the promoter region of the human VEGF-related factor gene.

@article{Silins1997AnalysisOT,
  title={Analysis of the promoter region of the human VEGF-related factor gene.},
  author={Ginters Silins and Sean B. Grimmond and Mark Egerton and Nicholas John Hayward},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={230 2},
  pages={413-8}
}
We have characterised the promoters of the human and murine VRF (vascular endothelial growth factor (VEGF) related factor) gene. A series of deletions were made of a 553-bp region 5' of the VRF initiation codon and were used in a luciferase reporter gene assay to determine the minimal promoter of the VRF gene. The region between base pairs -443 and -195 was sufficient to mediate transcription in lymphocytes and the region between -550 and -443 enhanced this promoter activity. Primer extension… CONTINUE READING
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