Analysis of the promoter region of human mimecan gene.

  title={Analysis of the promoter region of human mimecan gene.},
  author={Elena S. Tasheva},
  journal={Biochimica et biophysica acta},
  volume={1575 1-3},
Mimecan is a small leucine-rich proteoglycan (SLRP) that may play an important role in the regulation of cellular growth as illustrated by ability of growth factors and cytokines to modulate its expression and by recent demonstration that bovine mimecan is transcriptionally activated by p53 through a conserved intronic recognition site. To investigate transcriptional regulation of human mimecan, the upstream region and the first intron of this gene were cloned and analyzed. Within a 296-bp… CONTINUE READING


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