Analysis of the organization and nucleotide sequence of the chromosomal gene for the beta-subunit of rat thyrotropin.

@article{Croyle1986AnalysisOT,
  title={Analysis of the organization and nucleotide sequence of the chromosomal gene for the beta-subunit of rat thyrotropin.},
  author={Mickey Croyle and Alok Bhattacharya and David F. Gordon and Ruth A. Maurer},
  journal={DNA},
  year={1986},
  volume={5 4},
  pages={299-304}
}
The gene for the beta-subunit of rat thyrotropin has been isolated from a library of rat DNA fragments cloned in bacteriophage lambda. The complete nucleotide sequence of the gene has been determined including a portion of 5'- and 3'-flanking regions. The rat TSH-beta gene contains approximately 4879 nucleotides which ultimately lead to the production of a mRNA of about 554 nucleotides, exclusive of the 3' poly(A) tract. The first exon which represents only 5' untranslated sequences of the mRNA… CONTINUE READING