Analysis of the nitric oxide-sensing non-heme iron center in the NorR regulatory protein.

@article{Tucker2008AnalysisOT,
  title={Analysis of the nitric oxide-sensing non-heme iron center in the NorR regulatory protein.},
  author={Nicholas P. Tucker and B D'autr{\'e}aux and Faridoon K. Yousafzai and Shirley A. Fairhurst and Stephen Spiro and Ray Dixon},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 2},
  pages={908-18}
}
The NorR regulatory protein senses nitric oxide (NO) to activate genes required for NO detoxification under anaerobic and microaerobic conditions in Escherichia coli. NorR belongs to the sigma(54)-dependent family of transcriptional activators and contains an N-terminal regulatory GAF (cGMP phosphodiesterase, adenylate cyclase, FhlA) domain that controls the ATPase activity of the central AAA+ domain to regulate productive interactions with sigma(54). Binding of NO to a non-heme iron center in… CONTINUE READING

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Nitrous oxide production and consumption: regulation of gene expression by gas-sensitive transcription factors.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences • 2012

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