Analysis of the nature of antagonism of the reserpine-induced hypothermia by imipramine

Abstract

Antagonism of reserpine-induced hypothermia is an animal model used in the screening of antidepressants. The activity of imipramine on this test is partly impaired by propranolol. This effect of imipramine was analyzed using specific adrenoceptor and 5-HT receptor blocking drugs in order to determine the nature of this effect of propranolol. The non… (More)
DOI: 10.1007/BF00172682

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@article{Francs1987AnalysisOT, title={Analysis of the nature of antagonism of the reserpine-induced hypothermia by imipramine}, author={Henriette Franc{\`e}s}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={1987}, volume={336}, pages={303-307} }