Analysis of the membrane domain of the gastric H(+)/K(+)-ATPase.


A structure of the catalytic or alpha subunit of the H(+)/K(+)-ATPase, with ten transmembrane segments, and of the beta subunit, with a single such segment, was established using a combination of tryptic cleavage and peptide sequencing and in vitro translation. Sites at which covalent ligands bind to external surfaces were also defined by cleavage… (More)


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@article{Munson2000AnalysisOT, title={Analysis of the membrane domain of the gastric H(+)/K(+)-ATPase.}, author={Kathleen M. Munson and Nathalie J. Lambrecht and J. M. Shin and G. Sachs}, journal={The Journal of experimental biology}, year={2000}, volume={203 Pt 1}, pages={161-70} }