Analysis of the mechanism of asymmetric amplification by chiral auxiliary trans-1,2-diaminocyclohexane bistriflamide.

Abstract

Asymmetric amplification is a phenomenon in which the enantiomeric excess (ee) of a product is higher than that of a chiral auxiliary for a catalyst. We analyzed the mechanism of asymmetric amplification observed in the addition of diethylzinc (Et(2)Zn) to benzaldehyde (PhCHO) to synthesize 1-phenyl-1-propanol in the presence of trans-1,2-diaminocyclohexane… (More)
DOI: 10.1002/chir.20563

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@article{Asakura2008AnalysisOT, title={Analysis of the mechanism of asymmetric amplification by chiral auxiliary trans-1,2-diaminocyclohexane bistriflamide.}, author={Kouichi Asakura and Yuuki Isoda and Dilip Kondepudi and Tomohiko Yamaguchi}, journal={Chirality}, year={2008}, volume={20 8}, pages={919-23} }