Analysis of the marble burying response: marbles serve to measure digging rather than evoke burying.

@article{Gyertyn1995AnalysisOT,
  title={Analysis of the marble burying response: marbles serve to measure digging rather than evoke burying.},
  author={Istv{\'a}n Gyerty{\'a}n},
  journal={Behavioural pharmacology},
  year={1995},
  volume={6 1},
  pages={24-31}
}
Marble burying has been suggested as a model of obsessive-compulsive disorder (OCD) based on the fact that specific serotonin reuptake inhibitors selectively influenced this response. Studying the behaviour we observed that mice also exhibited intense digging activity in the absence of glass marbles. This digging activity showed no habituation either between sessions or within a session, and it could be inhibited by psychotropic drugs in a manner similar to the marble burying response. On the… CONTINUE READING

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