Analysis of the interleukin-12/interferon-γ pathway in children with non-tuberculous mycobacterial cervical lymphadenitis

@article{Serour2006AnalysisOT,
  title={Analysis of the interleukin-12/interferon-$\gamma$ pathway in children with non-tuberculous mycobacterial cervical lymphadenitis},
  author={Francis Serour and Avraham Mizrahi and Eli Somekh and Jacqueline Feinberg and Capucine Picard and Jean Laurent Casanova and Ila De Dalal},
  journal={European Journal of Pediatrics},
  year={2006},
  volume={166},
  pages={835-841}
}
Genetic defects along the interleukin (IL)-12/interferon (IFN)−γ pathway have been found in patients with mendelian susceptibility to mycobacterial disease (MSMD) caused by live BCG vaccine or non-tuberculous Mycobacterium (NTM) species, highlighting the crucial role of this axis in human immunity to Mycobacterium. The aims of this study were to characterize healthy children presenting with cervical lymphadenitis caused by NTM and to investigate their IL-12/IFN-γ pathway. Epidemiological… Expand
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