Analysis of the interaction of phytoestrogens and synthetic chemicals: an in vitro/in vivo comparison.

@article{Charles2007AnalysisOT,
  title={Analysis of the interaction of phytoestrogens and synthetic chemicals: an in vitro/in vivo comparison.},
  author={Grantley D. Charles and Chris Gennings and Belen M Tornesi and H Lynn Kan and Timothy R. Zacharewski and B Bhaskar Gollapudi and Edward W. Carney},
  journal={Toxicology and applied pharmacology},
  year={2007},
  volume={218 3},
  pages={280-8}
}
In the evaluation of chemical mixture toxicity, it is desirable to develop an evaluation paradigm which incorporates some critical attributes of real world exposures, particularly low dose levels, larger numbers of chemicals, and chemicals from synthetic and natural sources. This study evaluated the impact of low level exposure to a mixture of six synthetic chemicals (SC) under conditions of co-exposure to various levels of plant-derived phytoestrogen (PE) compounds. Estrogenic activity was… CONTINUE READING
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