Analysis of the humoral immune response to chlamydial genital infection in guinea pigs.

@article{Batteiger1987AnalysisOT,
  title={Analysis of the humoral immune response to chlamydial genital infection in guinea pigs.},
  author={Byron E. Batteiger and Roger G. Rank},
  journal={Infection and immunity},
  year={1987},
  volume={55 8},
  pages={1767-73}
}
Studies using the guinea pig model of chlamydial genital infection with the Chlamydia psittaci agent of guinea pig inclusion conjunctivitis (GPIC) have shown that serum and local antibodies play a role both in the resolution of infection and in protection against reinfection. Thus, this model is suited for further exploration of immune mechanisms and for vaccine studies with chlamydial macromolecules. We have further characterized the model by assessing the antigen-specific antibody response to… CONTINUE READING
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