Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin

@inproceedings{Petit2011AnalysisOT,
  title={Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin},
  author={Sarah J. Petit and Caroline Blondeau and Greg J. Towers},
  booktitle={The Journal of general virology},
  year={2011}
}
Zoonosis of chimpanzee simian immunodeficiency virus cpz to humans has given rise to both pandemic (M) and non-pandemic (O, N and P) groups of human immunodeficiency virus type-1 (HIV). These lentiviruses encode accessory proteins, including Vpu, which has been shown to reduce CD4 levels on the cell surface, as well as increase virion release from the cell by antagonizing tetherin (CD317, BST2). Here, we confirm that O group Vpus (Ca9 and BCF06) are unable to counteract tetherin or downregulate… CONTINUE READING
9 Citations
35 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Similar Papers

Loading similar papers…