Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

@article{Xie2003AnalysisOT,
  title={Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.},
  author={Tao Xie and Lee Rowen and Bego{\~n}a Aguado and Mary Ellen Ahearn and Anup Madan and Shizhen Qin and Robert D. Campbell and Leroy Hood},
  journal={Genome research},
  year={2003},
  volume={13 12},
  pages={2621-36}
}
In mammals, the Major Histocompatibility Complex class I and II gene clusters are separated by an approximately 700-kb stretch of sequence called the MHC class III region, which has been associated with susceptibility to numerous diseases. To facilitate understanding of this medically important and architecturally interesting portion of the genome, we have sequenced and analyzed both the human and mouse class III regions. The cross-species comparison has facilitated the identification of 60… CONTINUE READING

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