Analysis of the effects of cryopreservation on rat hepatocytes using SELDI-TOF mass spectrometry.

Abstract

Successful cryopreservation of hepatocytes is essential to the future of hepatocyte transplantation as a treatment for liver disease, and also for the improved in vitro use of hepatocytes for research. However, hepatocyte function is adversely affected by even the best cryopreservation protocols. To investigate possible mechanisms for these changes, total… (More)

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