Analysis of the distribution of human CD38 and of its ligand CD31 in normal tissues.

@article{Fernndez1998AnalysisOT,
  title={Analysis of the distribution of human CD38 and of its ligand CD31 in normal tissues.},
  author={Juan Emilio Vel{\'a}squez Fern{\'a}ndez and Silvia Deaglio and Davide Donati and Ivna Svoboda Beusan and Franco Del Corno and Amelia Eva Ar{\'a}nega and Monica Forni and Brunangelo Falini and Fabio Malavasi},
  journal={Journal of biological regulators and homeostatic agents},
  year={1998},
  volume={12 3},
  pages={
          81-91
        }
}
Human CD38 is a 45 kD ectoenzyme endowed with ADP-ribosyl cyclase and hydrolase activities. The molecule plays a central role in lymphocyte activation, proliferation and selectin-type adhesion with endothelial cells (HEC). A HEC surface molecule displaying all the features of a CD38L has been identified by means of a mAb (Moon-1), able to block CD38-mediated adhesion processes. The 130 kD molecule recognized by Moon-1 is CD31, a member of the Ig superfamily. This paper reports on the analysis… CONTINUE READING

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