Analysis of the degradation compounds of chemical warfare agents using liquid chromatography/mass spectrometry.

@article{Smith2001AnalysisOT,
  title={Analysis of the degradation compounds of chemical warfare agents using liquid chromatography/mass spectrometry.},
  author={J. Richard Smith and Ming L. Shih},
  journal={Journal of applied toxicology : JAT},
  year={2001},
  volume={21 Suppl 1},
  pages={S27-34}
}
The analysis of the degradation products of chemical warfare (CW) agents has been a challenge to analysts. The low volatility of these compounds makes them unsuitable for direct gas chromatography analysis without prior derivatization. Lack of a chromophore causes difficulties with classic detection methods after liquid chromatography separation. With the recent development of various interfaces that allow for the introduction of a liquid solvent stream into the mass spectrometer, the task of… CONTINUE READING