Analysis of the decaprenyl diphosphate synthase (dps) gene in fission yeast suggests a role of ubiquinone as an antioxidant.

@article{Suzuki1997AnalysisOT,
  title={Analysis of the decaprenyl diphosphate synthase (dps) gene in fission yeast suggests a role of ubiquinone as an antioxidant.},
  author={Katsunori Suzuki and Kiyoshi Okada and Yuji Kamiya and Xiao Fan Zhu and Tsuyoshi Nakagawa and Makoto Kawamukai and Hideyuki Matsuda},
  journal={Journal of biochemistry},
  year={1997},
  volume={121 3},
  pages={496-505}
}
Schizosaccharomyces pombe produces ubiquinone-10 whose side chain is thought to be provided by the product generated by decaprenyl diphosphate synthase. To understand the mechanism of ubiquinone biosynthesis in S. pombe, we have cloned the gene encoding decaprenyl diphosphate synthase by the combination of PCR amplification of the fragment and subsequent library screening. The determined DNA sequence of the cloned gene, called dps, revealed that the dps gene encodes a 378-amino-acid protein… CONTINUE READING
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