Analysis of the cytotoxic activity of carboplatin and gemcitabine combination.

@article{Wang2010AnalysisOT,
  title={Analysis of the cytotoxic activity of carboplatin and gemcitabine combination.},
  author={Sisi Wang and Hongyong Zhang and Liang Cheng and Christopher Evans and Chong-xian Pan},
  journal={Anticancer research},
  year={2010},
  volume={30 11},
  pages={4573-8}
}
AIM To determine if the drug doses and administration schedules of carboplatin and gemcitabine combination affect antitumor effects. MATERIALS AND METHODS The inhibition of cell viability was measured by MTT assay. Median effect analysis was conducted to determine the cytotoxicity activity of carboplatin and gemcitabine combination. Cell cycle changes were analyzed by flow cytometry. RESULTS Synergism was observed when the bladder cancer cell line 5637 cells were treated with gemcitabine… CONTINUE READING
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