Analysis of the cell-dependent replication potentials of human immunodeficiency virus type 1 vif mutants.

@article{Fujita2001AnalysisOT,
  title={Analysis of the cell-dependent replication potentials of human immunodeficiency virus type 1 vif mutants.},
  author={Mikako Fujita and Akiko Sakurai and Naoya Doi and Maki Miyaura and Akiko Yoshida and Kohei Sakai and Akio Adachi},
  journal={Microbes and infection},
  year={2001},
  volume={3 13},
  pages={1093-9}
}
Eleven in-frame vif gene mutants of HIV type 1 produced in non-permissive cells were examined for their replication potentials in various CD4-positive and -negative cell lines. Virus replication for each mutant was monitored by using several single- and multiple-cycle infectivity assays. Except for a mutant with wild-type phenotype, most mutants were… CONTINUE READING