Analysis of the cell and erythrocyte binding activities of the dimple and canyon regions of the canine parvovirus capsid.

@article{Tresnan1995AnalysisOT,
  title={Analysis of the cell and erythrocyte binding activities of the dimple and canyon regions of the canine parvovirus capsid.},
  author={Dina B Tresnan and L Southard and Wilko Weichert and Jennifer Sgro and Colin R Parrish},
  journal={Virology},
  year={1995},
  volume={211 1},
  pages={123-32}
}
Canine parvovirus (CPV) binds to a number of cell and erythrocyte receptors, some of which are involved in cell infection, while others are used for other viral functions. Little is known about the regions of the virus capsid which bind to the cell receptors. CPV binds sialic acid through a region within or adjacent to the dimple on the surface of the capsid (Barbis, D. P., Chang, S-F., and Parrish, C. R., 1992, Virology 191, 301-308). In order to map the sialic acid binding site in more detail… CONTINUE READING

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