Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.

@article{McCarrey1996AnalysisOT,
  title={Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.},
  author={John Robert McCarrey and Sukhbeer Kumari and Mary Jo Aivaliotis and Zhengxin Wang and Ping Zhang and Francis Marshall and John L Vandeberg},
  journal={Developmental genetics},
  year={1996},
  volume={19 4},
  pages={
          321-32
        }
}
Because of their unique function, germ cells require unique gene products. Thus, although the glycolytic enzyme phosphoglycerate kinase (PGK) is required in all metabolically active cell types, there are two functional PGK genes in the mammalian genome, one, PGK-1, that is X-linked and ubiquitously expressed in all somatic tissues, and a second, PGK-2, that is autosomal and expressed only in spermatogenic cells. Expression of the PGK-2 gene may function solely to compensate for repressed… CONTINUE READING
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