Analysis of the antigenic profile of measles virus haemagglutinin in mice and humans using overlapping synthetic peptides.

@article{Obeid1994AnalysisOT,
  title={Analysis of the antigenic profile of measles virus haemagglutinin in mice and humans using overlapping synthetic peptides.},
  author={Obeid El-Treify Obeid and Charalambos D. Partidos and Michael W. Steward},
  journal={Virus research},
  year={1994},
  volume={32 1},
  pages={69-84}
}
In this study, a panel of 55 synthetic peptides representing 92.2% of the haemagglutinin (H) glycoprotein of measles virus (MV) were used to study the antigenic profile of the H molecule of anti-MV antibodies raised in mice and late convalescent human sera. In addition the immunogenicity of these peptides was tested in two mouse strains. Mouse anti-MV antibodies had different fine specificity of binding to the peptides depending on the mouse strain. Thus in BALB/c (H-2d) mice, anti-MV… CONTINUE READING

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