Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.

  title={Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.},
  author={T Nicolai Siegel and Doeke R. Hekstra and George A. M. Cross},
  journal={Molecular and biochemical parasitology},
  volume={160 2},
Trypanosoma brucei has two DNA compartments: the nucleus and the kinetoplast. DNA replication of these two compartments only partially coincides. Woodward and Gull [Woodward R, Gull K. Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci 1990;95:49-57] comprehensively studied the relative timing of the replication and segregation of nuclear DNA (nDNA) and kinetoplast DNA (kDNA). Others have since assumed the… CONTINUE READING


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