Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier.

Abstract

PURPOSE The morphology of the RPE shows minimal change as the neural retina and choriocapillaris differentiate. Nonetheless, initial studies of proteins related to the outer blood-retinal barrier suggest extensive remodeling of the retinal pigment epithelium (RPE) in response to this changing environment. A genomic approach was used to investigate the… (More)

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