Analysis of the Piv recombinase-related gene family of Neisseria gonorrhoeae.

@article{Skaar2005AnalysisOT,
  title={Analysis of the Piv recombinase-related gene family of Neisseria gonorrhoeae.},
  author={Eric P Skaar and Brian Lecuyer and A G Lenich and Matthew P Lazio and Donna Perkins-Balding and H Steven Seifert and Anna C Karls},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 4},
  pages={
          1276-86
        }
}
Neisseria gonorrhoeae (the gonococcus) is an obligate human pathogen and the causative agent of the disease gonorrhea. The gonococcal pilus undergoes antigenic variation through high-frequency recombination events between unexpressed pilS silent copies and the pilin expression locus pilE. The machinery involved in pilin antigenic variation identified to date is composed primarily of genes involved in homologous recombination. However, a number of characteristics of antigenic variation suggest… CONTINUE READING

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