Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients.

@article{Price2000AnalysisOT,
  title={Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients.},
  author={Jennifer A. Price and Sallyanne C. Fossey and Michele M Sale and Catherine S Brewer and Barry I. Freedman and J P Wuerth and Donald W. Bowden},
  journal={Diabetologia},
  year={2000},
  volume={43 3},
  pages={364-72}
}
AIMS/HYPOTHESIS Linkage and association studies in Caucasian patients with Type II (non-insulin-dependent) diabetes mellitus suggest that one or more diabetes susceptibility gene(s) reside within human chromosome 20q12-13.1. This region of chromosome 20 contains the maturity-onset diabetes of the young type 1 gene, HNF4 alpha. The purpose of this study was to assess the possible involvement of HNF4 alpha in Type II diabetes. METHODS Mutation analysis was done on the 12 exons and promoter… CONTINUE READING

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