Analysis of synovial fluid in knee joint of osteoarthritis:5 proteome patterns of joint inflammation based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

@article{Pan2011AnalysisOS,
  title={Analysis of synovial fluid in knee joint of osteoarthritis:5 proteome patterns of joint inflammation based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry},
  author={Xiaohua Pan and L. Huang and Jiakai Chen and Y. Dai and Xiao-fen Chen},
  journal={International Orthopaedics},
  year={2011},
  volume={36},
  pages={57-64}
}
  • Xiaohua Pan, L. Huang, +2 authors Xiao-fen Chen
  • Published 2011
  • Medicine
  • International Orthopaedics
  • PurposeThe purpose of this study was to use matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) in osteoarthritis research. Our aim was to find differentially expressed disease-related and condition-specific peptide in synovial fluid in the knee joint of patients suffering from osteoarthritis (OA), and to develop and validate the peptide classification model for OA diagnosis.MethodsBased on the American College of Rheumatology criteria, 30 OA cases and… CONTINUE READING
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