Analysis of steroid conjugates in sewage influent and effluent by liquid chromatography-tandem mass spectrometry.

@article{Reddy2005AnalysisOS,
  title={Analysis of steroid conjugates in sewage influent and effluent by liquid chromatography-tandem mass spectrometry.},
  author={Sharanya Reddy and Charles R. Iden and Bruce J. Brownawell},
  journal={Analytical chemistry},
  year={2005},
  volume={77 21},
  pages={7032-8}
}
Environmental endocrine disruptors such as estrone (E1) and beta-estradiol (E2) are excreted in human urine primarily as water-soluble glucuronides and sulfates that can dissociate in wastewater treatment systems to the more active free estrogens. Measurement of the distribution and fate of the steroid conjugates and the corresponding free estrogens in treatment plants and receiving waters is critical for understanding the reproductive and developmental effects of these substances on aquatic… CONTINUE READING

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