Analysis of small intestinal transit and colon arrival times of non-disintegrating tablets administered in the fasted state.

@article{Pilar2015AnalysisOS,
  title={Analysis of small intestinal transit and colon arrival times of non-disintegrating tablets administered in the fasted state.},
  author={Mitja Pi{\vs}lar and Hana Brelih and Ale{\vs} Mrhar and Marija Bogataj},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2015},
  volume={75},
  pages={
          131-41
        }
}
In this study individual data on tablet gastrointestinal transit times (i.e. gastric emptying, small intestinal transit, ileocecal junction residence, and colon arrival times) were obtained from literature in order to present and analyze their distributions and relationships. The influence of the time of food intake after tablet administration in fasted state on gastrointestinal transit times was additionally evaluated. There were 114 measurements from subjects who received the first meal at 4h… CONTINUE READING

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