Corpus ID: 87225316

Analysis of single nucleotide polymorphisms of MTHFR and DPYD genes in pancreatic cancer cell lines

@inproceedings{Lu2011AnalysisOS,
  title={Analysis of single nucleotide polymorphisms of MTHFR and DPYD genes in pancreatic cancer cell lines},
  author={Cheng Tsung Lu},
  year={2011}
}
  • Cheng Tsung Lu
  • Published 2011
  • Biology
  • Objective To detect single nucleotide polymorphisms(SNPs) of two pharmacokinetics related genes in three pancreatic cancer cell lines in order to provide references for prediction clinical efficacy and toxicity of fluorouracil.Methods PANC-1,CFPAC and SW1990 cell lines were cultured.The genomic DNA of the two cell lines were isolated by QIAamp DNA Blood Minikit.SNP genotyping of DPYD gene rs1801159,rs1801160,rs17376848 and MTHFR gene rs1801131,rs1801133,rs2274976 was performed by means of… CONTINUE READING

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