Analysis of serum proteome profiles of non-Hodgkin lymphoma for biomarker identification.

  title={Analysis of serum proteome profiles of non-Hodgkin lymphoma for biomarker identification.},
  author={Ming Zhang and Zhen Chang Sun and Xiao Rui Fu and Fei Fei Nan and Qing Xia Fan and Xing Wu and Li Geng and W. Q. Ma and Rui Wang},
  journal={Journal of proteomics},
  volume={72 6},
Serum samples from non-Hodgkin lymphoma (NHL) patients who had not undergone chemotherapy, lymphnoditis patients, and healthy adults were analyzed using surface-enhanced laser desorption-ionization time-of-flight mass spectrometry (SELDI-TOF MS) to detect the differentially expressed serum proteins. Models were developed to distinguish between the healthy adult group and the NHL group, with a sensitivity of 69% and specificity of 90%, and between the lymphnoditis group and the NHL group with a… CONTINUE READING


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Detection of IgH rearrangement in B cell lymphoma patients' peripheral blood

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